Antiendothelial cell antibodies detected by a cellular based ELISA in Kawasaki disease.
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چکیده
منابع مشابه
Antiendothelial cell antibodies detected by a cellular based ELISA in Kawasaki disease.
Kawasaki disease is an acute vasculitic illness of childhood associated with significant morbidity and mortality. A cellular based enzyme linked immunosorbent assay (ELISA) was used to demonstrate the presence of antiendothelial cell antibodies in sera from children with Kawasaki disease. Twenty one of 32 patients with Kawasaki disease had raised IgM antibody titres and four had raised IgG anti...
متن کاملComparison of cell-ELISA, flow cytometry and Western blotting for the detection of antiendothelial cell antibodies.
OBJECTIVE There is still great uncertainty in the detection of antiendothelial cell antibodies (AECA). The aim of our study was to compare the results obtained using different methods. METHODS Sera were obtained from 71 patients with a variety of vasculitides. Three assay methods were used: cell ELISA, flow cytometry (FACS) and Western blot (WB). RESULTS In the ELISA 12/17 patients with sys...
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SUMMARY: Kawasaki is an acute multisystemic disease affecting Predominantly. Children below 4 years of age. Having a Self- limited Course, it often Presents as Vasculitis. The Principal Complications are Stomatitis, conjunctivitis. Lymphadenopathy, Skin rashes as well as involvment of cardiovascular, alimentary and nervous system. In this article we report the First case of Kawasaki Disease ...
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The prevalent ages at onset for Kawasaki Disease (KD) and Epstein-Barr virus (EBV) infection are known to be similar in Korea and Japan. We evaluated the correlation between EBV infection and KD. The antibodies to EBV such as anti-viral capsid antigen (VCA) IgG and IgM, anti-diffuse and restricted early antigen IgG (anti-EADR IgG), and the anti-EBV determined nuclear antigen IgG (anti-EBNA IgG)...
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Autoantibodies against components of neutrophil cytoplasm develop during adult vasculitic diseases such as Wegener's granulomatosis and microscopic polyarteritis, and they are predominantly of the IgG class. Similar but distinct antibodies have been described in children with Kawasaki disease and both IgM and IgG class antibodies are represented. This adds another clinically distinct childhood ...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1991
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.66.2.189